09/18/17


FDA Approves Symbiomix Therapeutics’ Solosec™ (secnidazole) Oral Granules for the Treatment of Bacterial Vaginosis in Adult Women

Segal’s Dr. Chavoustie worked on phase 2 and 3 of the clinical trials for Solosec – the First and Only Single Dose Oral Therapy Approved for Most Common U.S. Gynecologic Infection That Can Have Serious Health Risks if Inadequately Treated.

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Dr. Chavoustie completed his undergraduate studies at the University of Miami in Coral Gables, Florida. He graduated Magna Cum Laude with a Bachelor of Science in Chemistry and received his MD degree from the University of Miami School of Medicine. He participated in multiple externships before completing an internship and residency in obstetrics and gynecology at Jackson Memorial Hospital. He then served as the Administrative Chief Resident from 1984 to 1985. He is a fellow of the American College of Obstetrics and Gynecology and is a Certified Clinical Research Professional with SOCRA.
 
Dr. Chavoustie joined Segal Trials as an Investigator in 2007. He has conducted and continues to conduct clinical research trials in the area of most women’s health, general medicine and addiction medicine. His expertise with implantable drug delivery systems led him to be the Implant Medical Monitor for several Phase Ill clinical trials.

06/21/17


Dr. Chavoustie authors Expert Review of Clinical Pharmacology on Buprenorphine implants in medical treatment of opioid addiction

Segal’s very own, Dr. Steven Chavoustie, authors an article, “Buprenorphine implants in medical treatment of opioid addiction,” which was recently published in the Expert Review of Clinical Pharmacology.

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05/12/17


Researchers find nutritional supplement could help children with autism

Segal Trials’, Dr. Scott Segal, was interviewed about his research on Curemark’s autism trial.

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05/12/17


Segal Trials is proud to support CISCRP in the latest USA Today supplement on Clinical Trials, released to raise the visibility of clinical research among patients and the public.

In Segal Trials continued effort to support patient engagement and clinical research awareness programs, we are proud to support CISCRP’s newly launched National Clinical Trial Outreach and Awareness Initiative to raise the visibility of clinical research and elevate the level of public and patient preparedness to navigate the clinical research process. As part of this initiative, we have collaborated with CISCRP to sponsor the release of a Clinical Trials supplement in the latest edition of USA Today.

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04/26/17


Braeburn Pharmaceuticals Achieves Primary Endpoint in Pivotal Phase 2/3 Study of BB0817, Risperidone 6-month Implant for Treatment of Schizophrenia

Segal Trials Associate Medical Director and Principal Investigator of the trial, Dr. Rishi Kakar, is mentioned in Braeburn’s press release. “Compliance with medication is a very important clinical issue, and without it, serious consequences including relapse and hospitalization are more likely. Preventing non-compliance is an important goal for any successful clinical treatment.”

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04/11/17


FDA approves first drug to treat tardive dyskinesia

Segal Trials’ Dr. Rishi Kakar, Dr. Scott Segal, and Dr. Eduardo Cifuentes are proud have worked on the clinical trials that brought this medication to market.

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03/23/17


A toxic combination of declining social status, poor health and failed relationships is being blamed

Segal’s very own, Dr. Rishi Kakar, was interviewed by the Washington Times discussing the link between poor socio-economic support and addiction. “A lot of these individuals do not have proper access to treatment for their opioid addiction,” Kakar says.

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03/06/17


Dr. Chavoustie co-authors consensus statement titled “State of Bacterial Vaginosis: Experts Explore Unmet Needs Facing Women and Providers”

Segal’s Dr. Steven Chavoustie helped to author the research paper, “Experts explore the state of bacterial vaginosis and the unmet needs facing women and providers,” recently published in the International Journal of Gynecology & Obstetrics.

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11/29/16

usatoday

CISCRP recognizes Segal’s commitment at this year’s AWARE for All event with a USA Today supplement as a supporter of Medical Heroes

As part of Segal’s continued efforts to support patient engagement and patient-centric initiatives, we are proud to share an advertisement that is running in the latest issue of USA Today, recognizing Medical Heroes – study volunteers who participate in clinical research – for their contribution to the future of medicine. This is an advertisement that CISCRP runs on an annual basis and we are happy to be a sponsor of this year’s important message: Thank You to the men and women who take part in clinical research for not only advancing knowledge about disease, but also improving medical treatments for generations to come.

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11/17/16

fda

FDA approves Intrarosa for postmenopausal women experiencing pain during sex

Segal’s Dr. Chavoustie worked on phase 2 and 3 of the clinical trials for Intrarosa (prasterone). The U.S. Food and Drug Administration approved Intrarosa (prasterone) to treat women experiencing moderate to severe pain during sexual intercourse (dyspareunia), a symptom of vulvar and vaginal atrophy (VVA), due to menopause….

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10/10/16


Dr. Chavoustie Featured in WIRED

Dr. Chavoustie was recently featured in WIRED magazine addressing America’s horrific opioid epidemic.

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8/25/16

starr

Meet Dr. Rishi Kakar

Dr. Rishi Kakar is Segal Trials Principal Investigator and Associate Medical Director, he’s also the Principal Investigator at Atlantic Shores Hospital and the West Broward Outpatient Clinic, and maintains an active private practice with Compass Health Systems.

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8/2/16

forbes

Are Clinical Trial Sites Leaving Billable Items on the Table?

Bonnie Segal was interviewed by ACRP on how sites often leave money for billable activities on the negotiating table. “When it comes to negotiating a contract on behalf of a site, there’s no room anymore for someone who is not on their game,” Segal says.

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7/19/16

forbes

Effect of Buprenorphine Implants on Illicit Opioid Use Among Abstinent Adults With Opioid Dependence Treated With Sublingual Buprenorphine

The PRO-814 Study Group investigators include Segal Trials’ own Eduardo Cifuentes, MD, Scott Segal, MD, and Rishi Kakar, MD.

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7/12/16

forbes

Coalition Offers Ideas for Raising Trial Awareness

“The average patient has little knowledge about what it means to participate in a clinical trial, and that’s a problem.” At Segal Trials, we are working on these key ideas to help increase public awareness and education regarding clinical research trials.

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7/1/16

forbes

How The Marketing Of Clinical Trials Saves Lives

We applaud Forbes positive outlook on the importance of clinical trial marketing. Our own Dr. Segal articulated the challenges associated with the recruitment process. Well done Forbes!

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6/20/16

braeburn

Seventeen Days after Receiving FDA Approval, Braeburn Pharmaceuticals Announces First Patients Have Received Probuphine® (buprenorphine) Implant

Our own Dr. Chavoustie was the first in the country to implant a patient with Probuphine, since it’s recent FDA approval in May 2016. In Braeburn’s press release, Dr. Chavoustie, who collaborated with the FDA to finalize the training program on the procedures, said that “The large number of qualified healthcare providers signing up for the Probuphine trainings is proof that the medical community sees the potential this new option may offer their patients,” said Dr. Chavoustie who collaborated with the FDA to finalize the training program on the procedures.

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6/3/16

whdt

Is an Implant the Solution to the Opioid Epidemic?

Watch this informative interview with Dr. Segal and a study volunteer as they speak about their experience with the newly FDA approved opioid implant.

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6/3/16

newtimes

Implant Tested in Miami to Treat Opiate Addiction Gains FDA Approval

“Patients do very well on the implant,” Segal says. “It takes relapse off the table for six months, so it’s not a constant daily struggle anymore.”

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6/1/16

starr

Bonnie Segal Podcast

Bonnie Segal, Vice President and Co-founder of Segal Trials for Clinical Trials, discusses our work in the area of community outreach. With our dedicated team surrounding her, she pursues her vision of research education, collaboration and advocacy. Listen in as she explains the challenges and triumphs in this important endeavor.

Listen to the Podcast

5/31/16

braeburn

Braeburn Pharmaceuticals Announces Commercialization Plans for Probuphine® (buprenorphine) Implant, Six-Month Treatment for Opioid Dependence

The architect of the training program, Dr. Steven Chavoustie, gynecologist at the Segal Trials, Miami, and Braeburn Pharmaceuticals collaborated with the FDA to finalize the training program on the procedures.

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5/26/16

fda

FDA approves first buprenorphine implant for treatment of opioid dependence

Segal Trials is proud to have worked on the clinical trials that brought this implant to market, but more importantly we are thrilled that individuals will be helped by this extraordinary implant.

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5/26/16

healthday

FDA Approves Implant to Battle Opioid Addiction: Experts say steady dosing eliminates need to take medication daily to combat heroin, powerful painkillers

“It really reduces or eliminates cravings, and they don’t start searching around for opiates,” said Dr. Scott Segal, president and chief medical officer of the Segal Trials in Miami, one of the centers that participated in the clinical trials.

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5/24/16

miamiherald

Could this implant be the new weapon against opioid, heroin addiction?

This week, the FDA could approve Braeburn Pharmaceuticals’ buprenorphine implant, which provides up to six months continuous treatment for the withdrawal symptoms and cravings of opioid dependence. Courtesy of Braeburn Pharmaceuticals

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5/23/16

local

FDA expected to approve new alternative help for people addicted to drugs

Our own Dr. Segal was interviewed in this segment regarding the implant expected to receive FDA approval this month.

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2/19/16

braeburn

Opioid Dependence PSA

This is an unforgettable & eye-opening PSA on opioid dependence & addiction. Segal Trials Dr. Steven Chavoustie, participated in this powerful PSA. Thanks to all of our Principal Investigators: Dr. Scott Segal, Dr. Rishi Kakar, Dr. Steven E. Chavoustie, Dr. Olga Lapeyra and Dr. Eduardo Ciffuentes for participating in our numerous opioid dependence studies.

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2/5/16

wsvn

Shot at Redemption: New implant designed locally to treat opiate addiction

WSVN — For those battling an addiction to prescription painkillers, it can be difficult to see a light at the end of the tunnel. Now local researchers say a tiny implant could prove to be a big…

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1/12/16

usa

Panel recommends FDA approve implant to treat opiate addiction

An advisory committee recommended Tuesday that the Food and Drug Administration (FDA) approve an implant designed to reduce addicts’ cravings for heroin or prescription…

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12/30/15

braeburn

Braeburn Pharmaceuticals and Camurus Enroll First Patient in a Phase 3 Efficacy Trial of Long-acting Treatment for Opioid Dependence

Pharmaceuticals and Camurus announce that the first patient has been randomized in the double blind Phase 3 efficacy trial of CAM2038 in opioid-dependent patients.CAM2038 medications are designed for…

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10/8/15

neuro

Neurocrine Announces Positive Results from Phase III Kinect 3 Study of NBI-98854 in Tardive Dyskinesia

Neurocrine Biosciences, Inc. (NASDAQ: NBIX) announced today that NBI-98854, a highly selective small molecule VMAT2 inhibitor, showed a statistically significant reduction in tardive…

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April 2015

ascp

Metronidazole Vaginal Gel 1.3% in the Treatment of Bacterial Vaginosis: A Dose-Ranging Study

Objective: Metronidazole vaginal gel (MVG) 0.75% is a US Food and Drug Administration–approved, 5-day treatment for bacterial vaginosis (BV). This study tested the hypothesis that …

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2015

lilly

A Selective Nociceptin Receptor Antagonist to Treat Depression: Evidence from Preclinical and Clinical Studies

Nociceptin/Orphanin FQ (N/OFQ) is a 17 amino acid peptide that binds to the N/OFQ peptide (NOP) receptor (Reinscheid et al, 1995; Meunier et al, 1995). The NOP receptor is expressed in widespread areas of the…

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August 2013

ssa

Buprenorphine Implants for Treatment of Opioid Dependence: Randomized Comparison to Placebo and Sublingual Buprenorphine/Naloxone.

Based on substantial efficacy data, international guidelines specify sublingual buprenorphine and methadone as first-line treatments of opioid dependence [1]. Buprenorphine can be prescribed in office-based physi…

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