Outpatient Adult CNS & Addiction
Segal Trials Board-Certified and Board-Eligible Adult Psychiatrists conduct Phase I-IV outpatient research studies for most central nervous system disorders and addiction disorders. Segal Trials’ success is largely due to the volume of patients seen by the clinicians at its sister company, Compass Health Systems. Compass Health Systems is the largest provider of mental health services in each of the communities where its practices are located. The outpatient practices and outpatient research sites are located in Charleston and South Florida.
The South Florida Compass Health Systems network of over 60 professionals routinely refers subjects to the Segal Trials South Florida Principal Investigators. In 2016, more than 6,000 adults were treated for CNS and addiction disorders at the 5 South Florida Compass Health Systems outpatient offices. Currently, more than 80 new patients are seen each week. The vast number of patients seen at Compass combined with a population of 4,000,000 in South Florida enables unprecedented subject recruitment at the South Florida Segal Trials outpatient sites.
In South Carolina, the Compass Carolina Health Systems network of 10 clinicians saw approximately 1,100 adult outpatients in 2016. South Carolina is home to 8 major military bases, including those serving the Marines, the Army, the Navy, the Air Force, and the Coast Guard. The large population of military personnel in the area has contributed to a high number of reported outpatient cases of anxiety disorders, such as PTSD, and addiction in Charleston. Segal Trials has research offices directly on site at the Compass Carolina clinic facilitating subject enrollment.
Outpatient Adult CNS & Addiction Sites:
Outpatient Pediatric and Adolescent CNS & Addiction
Segal Trials Board-Certified and Board-Eligible Adolescent and Child Psychiatrists conduct Phase II-IV outpatient research studies for most central nervous system disorders affecting pediatrics and adolescents. Similar to its success with the adult population, Segal Trials’ vast subject recruitment is largely due to the large volume of patients treated by the clinicians at its sister company, Compass Health Systems.
In 2016, approximately 2,000 pediatric and adolescent patients visited Compass Health Systems South Florida outpatient clinics and around 400 pediatric and adolescent patients sought treatment at Compass Carolina Health Systems.
Outpatient Pediatric and Adolescent CNS & Addiction Sites:
Outpatient Geriatric CNS
The Principal Investigators at the Segal Trials South Florida sites conduct Phase II-IV outpatient research studies for most central nervous system disorders affecting geriatrics. The clinicians at South Florida Compass outpatient clinics saw more than 400 geriatric outpatients in 2016. Depression, mood disorders and insomnia are very common within this age group, but Alzheimer’s disease is the most commonly reported CNS disorder at the Compass outpatient sites.
Outpatient Geriatric CNS Sites:
Outpatient General Medicine & Women’s Health
The Principal Investigators at Segal Trials’ North Miami site proudly conduct outpatient Phase II-IV research studies for most general medicine and women’s health conditions. Board-Certified gynecologists and family medicine physicians specialize in a broad spectrum of disorders. Segal Trials’ recruitment success in these niche areas is largely due to the large volume of patients seen by the clinician network at its sister company, Compass Health Systems. With over 6,000 patients seen in 2016 at the 5 Compass Health Systems outpatient clinics, many have been recruited into general medicine and women’s health trials. The patients at Compass Health Systems have reported a wide range of women’s health conditions, including human papilloma virus, sexual dysfunction, vasomotor menopausal symptoms and bacterial vaginosis. Patients visiting the Compass clinics have also been afflicted with many general medical conditions including diabetes mellitus, osteoarthritis, overactive bladder syndrome, fibromyalgia, erectile dysfunction and hypertension. The Compass patient pool, the diversity of South Florida and its population of over 4,000,000 have enabled the Segal Trials’ women’s health and general medicine department to flourish.
Outpatient General Medicine & WH Sites:
Inpatient Adult CNS, General Medicine, & Addiction
Segal Trials Board-Certified and Board-Eligible Adult Psychiatrists conduct Phase I-IV inpatient research studies for most adult CNS and addiction disorders. Segal Trials’ success is largely due to the large volume of patients seen by the clinician network at its sister company, Compass Health Systems. Compass Health Systems is the largest provider of mental health services in each of the communities where its practices are located. Segal Trials’ inpatient sites are located in all of the regions where Compass Health Systems has practices, including Larkin Community Hospital in South Florida and Palmetto Lowcountry Behavioral Health in Charleston. All of the Segal Trials inpatient facilities can defer to a central Institutional Review Board.
In South Florida, Compass Health Systems Psychiatrists saw more than 5,000 adult inpatients in 2016. The Compass Health practitioners have privileges in approximately 20 area hospitals and see almost 300 inpatients each day. The most common disorders treated are depression, schizophrenia, psychotic disorders, mood disorders and addiction. Segal Trials’ Principal Investigators conduct inpatient studies at the psychiatric hospital, Larkin Community Hospital. Both of these sites are JCAHO-accredited and have dedicated research beds and research offices. Each site is equipped with specialized equipment for inpatient research studies, along with DSL lines, offices for cognitive testing, CLIA-waived lab processing areas, private offices for consenting subjects and monitor rooms.
The psychiatrists at Compass Carolina saw approximately 2,000 inpatients in 2016. The primary inpatient facility served by the Compass Carolina Psychiatrists is Palmetto Lowcountry Behavioral Health. The JCAHO-accredited site has 110 total beds, a partial hospitalization program and residential treatment center. The Segal Trials team has conducted over 25 inpatient research studies at the site.
Inpatient Adult CNS, General Medicine & Addiction Sites:
Inpatient Pediatrics and Adolescent CNS & Addiction
Segal Trials Board-Certified and Board-Eligible Child and Adolescent Psychiatrists conduct Phase I-IV inpatient research studies for most CNS and addiction disorders affecting the pediatric and adolescent populations. Segal Trials’ success is largely due to the large volume of patients seen by the clinician network at its sister company, Compass Health Systems. Compass Health Systems is the largest provider of mental health services in each of the communities where its practices are located. Segal Trials’ inpatient sites specializing in CNS and Addiction disorders for Pediatric & Adolescent patients are located in South Florida and South Carolina including Palmetto Lowcountry Behavioral Health. The Compass Carolina psychiatrists rendered psychiatric services to approximately 400 children.
Inpatient Pediatric & Adolescent CNS & Addiction Sites:
Phase I Studies
Segal Trials has experience in conducting a variety of Phase I studies, including bioavailability, bioequivalency, drug-to-drug interaction, QTc interval evaluations and Pharmacokinetic studies. Segal Trials’ Investigators and staff are capable of conducting these studies in special populations and manage a broad range of patients who can be rapidly enrolled in clinical trials.
Segal Trials’ Phase I studies are solely conducted in South Florida at Atlantic Shores Hospital, a 74 bed free-standing psychiatric hospital. Segal Trials Principal Investigators conduct Phase I studies in special populations on a segregated, 18-bed locked unit. A team of experienced coordinators, research assistants and phlebotomists support the Segal Trials Investigators 24-hours a day, seven days a week to ensure patient retention and safety. An on-site pharmacy and research offices with designated areas for testing, consenting, lab draws, physical exams and ECGs enable the team to take on a variety of Phase 1 studies. The site is equipped with specialized equipments including a -70° C freezer with an alarm system, -20° C freezer, refrigerators, centrifuges, refrigerated centrifuges, reclining shares for infusion therapy, ECG machines, stadiometer, glove box and synchronized wall clocks throughout the unit. Common areas have televisions, movies, ping pong, pool tables and arts and crafts activities. Additionally, subjects can enjoy the site’s locked, lushly landscaped outdoor courtyard with volleyball nets and basketball courts. In 2009, Segal Trials set up a 4-bed sleep lab directly on the unit in order to conduct highly specialized polysomnography studies involving acute populations. All Phase 1 studies are conducted in strict adherence to Segal Trials’ Phase 1 Standard Operating Procedures.
Phase 1 Study Sites:
Nursing Homes & Assisted Living Facilities
Segal Trials Investigators conduct Phase I-IV research studies for most medical and CNS conditions affecting geriatric patients residing in nursing homes. Segal Trials’ success in conducting nursing home trials is largely due to the Optimum Aging program at Compass Health Systems. Optimum Aging is comprised of a group of psychiatrists, internists and therapists that specialize in servicing nursing home patients in South Florida. Over 75 nursing homes and assisted living facilities contract with Compass’ Optimum Aging program enabling Segal Trials unparalleled access to this niche population.
Since the oldest Baby Boomers (born 1946-1964) turned 60 years old in 2006, Florida’s population of people aged 60+ years has grown to 23%. Florida is currently ranked the number one state in the United States for people aged 65+ years, with 16.8% of its population falling into that category. According to recent studies, the older population will be increasing dramatically in the next 18 years. The number of people aged 65+ years is expected to reach 71.5 million by 2020, compared to 35 million in 2000. In Florida alone, the older population of people aged 65+ years is expected to reach 19.5% in 2015 and 27.1% in 2030. (This is compared to 17.6% in 2000.) Furthermore, the longevity of this population is also increasing, thus people are living longer for a greater period of time than any other time in history. Consequently, the need to find treatment for disorders such as Alzheimer’s disease, Parkinson’s disease and hypertension is increasing at the same rate. The Segal Trials Investigators conducting research in nursing homes are proud to play an important role in the advancement of treatment options in this growing segment of our population.
In 2007, Segal Trials established a relationship with a large sleep laboratory vendor in South Florida, Sleep Disorder Solutions. Since its inception in 2002, Sleep Disorder Solutions has conducted over 40 industry-sponsored clinical research trials for a wide array of sleep disorders including chronic insomnia, sleep apnea and restless leg syndrome. With three free-standing sleep labs in South Florida, Segal Trials has successfully conducted Phase I-III research trials involving polysomnography in the pediatric, adolescent, adult, and geriatric populations.
Sleep Disorder Solutions sleep laboratories are equipped with an average of 5 beds, infrared cameras, Alice 5 software, sound- and light-insulated rooms, temperature-controlled rooms, ECG machines, -20° C freezer with temperature monitor, and centrifuges. Additionally, these labs offer two-way communication between patient and lab personnel, as well as office areas for administrative purposes, locked storage area, and a CLIA waived lab area facilitating the execution of many clinical research studies. Registered technicians score the studies in accordance with sponsor-specific protocols. All of the Sleep Disorder Solutions laboratories are Clinilabs and Henry Ford certified.
Sleep Studies Sites: