Study Links Hot Flashes to Changes in Blood Vessels of the Brain

photo courtesy of photokanok/
photo courtesy of photokanok/


In a new pilot study, researchers discovered that women who experience more frequent hot flashes show changes in brain scans associated with a higher risk for cerebrovascular diseases.

Past research has found connections between hot flashes and heart disease, but this study looks at hot flashes’ effect on blood flow problems in the brain specifically. The researchers recruited 20 middle-aged women and tracked their hot flashes over 24 hours with a device that measures skin conductance. They also took MRI scans of the women’s brains to look for white matter hyper-intensities, which scientists believe develop because of diseased blood vessels.

On average, the women reported three hot flashes per day; however, the devices counted an average of eight hot flashes per day. These unreported hot flashes likely occurred in the women’s sleep. The scientists found that women who had more hot flashes, especially while asleep, also had more white matter hyper-intensities.

“Other factors like age and cardiovascular risk factors did not explain this effect, so these findings suggest there is a relationship between menopausal hot flashes and blood vessel changes in the brain,” said principal investigator Dr. Rebecca Thurston. “Further work is needed to understand whether one causes the other, or if hot flashes are a signal of some other vascular process that impacts brain health.”

Do you suffer from frequent hot flashes? See if you qualify for Segal Institute’s clinical research study on hot flashes today!


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